Medrossiprogesterone [Dcit]
Brand names,
Medrossiprogesterone [Dcit]
Analogs
Medrossiprogesterone [Dcit]
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Medrossiprogesterone [Dcit]
Chemical_Formula
C22H32O3
Medrossiprogesterone [Dcit]
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medrossiprogesterone [Dcit]
fda sheet
Medrossiprogesterone [Dcit]
msds (material safety sheet)
Medrossiprogesterone [Dcit]
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medrossiprogesterone [Dcit]
Molecular Weight
344.488 g/mol
Medrossiprogesterone [Dcit]
Melting Point
220 - 223.5 oC
Medrossiprogesterone [Dcit]
H2O Solubility
22.2mg/L
Medrossiprogesterone [Dcit]
State
Solid
Medrossiprogesterone [Dcit]
LogP
3.606
Medrossiprogesterone [Dcit]
Dosage Forms
Tablets; Depo injection
Medrossiprogesterone [Dcit]
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medrossiprogesterone [Dcit]
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medrossiprogesterone [Dcit]
Absorption
Rapidly absorbed from GI tract
Medrossiprogesterone [Dcit]
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medrossiprogesterone [Dcit]
Patient Information
Medrossiprogesterone [Dcit]
Organisms Affected
Humans and other mammals